butabarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Coadministration of CYP3A4 inducers may lessen sufentanil stages and efficacy, perhaps precipitating withdrawal syndrome in people who've designed Bodily dependence to sufentanil. Discontinuation of concomitantly made use of CYP3A4 inducers may improve sufentanil plasma concentration.

butabarbital will reduce the level or impact of conivaptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

Working with this drugs with any of the following may well trigger an increased threat of specified Unintended effects but may very well be unavoidable in some instances. If employed jointly, your doctor might change the dose or how frequently you employ this medication, or Offer you Specific Guidelines about the use of foodstuff, Liquor, or tobacco.

butabarbital will minimize the extent or effect of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Pitolisant exposure is diminished by 50% if coadministered with strong CYP3A4 inducers.

Perampanel: Could enhance the CNS depressant outcome of CNS Depressants. Administration: Individuals getting perampanel with any other drug which has CNS depressant things to do must avoid sophisticated and substantial-chance things to do, specially People which include driving that need alertness and coordination, until eventually they have knowledge working with The mix. Think about therapy modification

buprenorphine subdermal implant and butabarbital both of those boost sedation. Stay away from or Use Alternate Drug. Restrict use to people for whom option remedy solutions are insufficient

butabarbital will lower the level or outcome of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

butabarbital will lower the level or effect of exemestane by influencing hepatic/intestinal enzyme CYP3A4 check here metabolism. Use Caution/Keep track of. For patients acquiring exemestane that has a potent CYP3A4 inducer the proposed dose of exemestane is 50 mg day by day after a food.

The existence of other health care problems may have an impact on using this medicine. Make sure you inform your medical doctor When you have almost every other medical problems, Specially:

butabarbital will decrease the level or effect of clarithromycin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.

butabarbital will minimize the level or influence of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. The efficacy of hormonal contraceptives might be minimized. Usage of a nonhormonal contraceptive is suggested.

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butabarbital will reduce the level or impact of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.

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